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Prolonged outbreak of New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE), Tuscany, Italy, 2018 to 2019.

Authors :
Tavoschi L
Forni S
Porretta A
Righi L
Pieralli F
Menichetti F
Falcone M
Gemignani G
Sani S
Vivani P
Bellandi T
Tacconi D
Turini L
Toccafondi G
Privitera G
Lopalco P
Baggiani A
Gemmi F
Luchini G
Petrillo M
Roti L
Pezzotti P
Pantosti A
Iannazzo S
Mechi MT
Rossolini GM
Source :
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin [Euro Surveill] 2020 Feb; Vol. 25 (6).
Publication Year :
2020

Abstract

In Tuscany, Italy, New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE) have increased since November 2018. Between November 2018 and October 2019, 1,645 samples were NDM-CRE-positive: 1,270 (77.2%) cases of intestinal carriage, 129 (7.8%) bloodstream infections and 246 (14.9%) infections/colonisations at other sites. Klebsiella pneumoniae were prevalent (1,495; 90.9%), with ST147/NDM-1 the dominant clone. Delayed outbreak identification and response resulted in sustained NDM-CRE transmission in the North-West area of Tuscany, but successfully contained spread within the region.

Details

Language :
English
ISSN :
1560-7917
Volume :
25
Issue :
6
Database :
MEDLINE
Journal :
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Publication Type :
Academic Journal
Accession number :
32070467
Full Text :
https://doi.org/10.2807/1560-7917.ES.2020.25.6.2000085