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Prolonged outbreak of New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE), Tuscany, Italy, 2018 to 2019.
- Source :
-
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin [Euro Surveill] 2020 Feb; Vol. 25 (6). - Publication Year :
- 2020
-
Abstract
- In Tuscany, Italy, New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE) have increased since November 2018. Between November 2018 and October 2019, 1,645 samples were NDM-CRE-positive: 1,270 (77.2%) cases of intestinal carriage, 129 (7.8%) bloodstream infections and 246 (14.9%) infections/colonisations at other sites. Klebsiella pneumoniae were prevalent (1,495; 90.9%), with ST147/NDM-1 the dominant clone. Delayed outbreak identification and response resulted in sustained NDM-CRE transmission in the North-West area of Tuscany, but successfully contained spread within the region.
- Subjects :
- Adolescent
Adult
Aged
Aged, 80 and over
Child
Child, Preschool
Drug Resistance, Multiple, Bacterial drug effects
Female
Humans
Infant
Infant, Newborn
Italy epidemiology
Klebsiella Infections drug therapy
Klebsiella pneumoniae enzymology
Klebsiella pneumoniae metabolism
Male
Microbial Sensitivity Tests
Middle Aged
Young Adult
beta-Lactamases drug effects
beta-Lactamases genetics
Anti-Bacterial Agents pharmacology
Carbapenems pharmacology
Disease Outbreaks
Klebsiella Infections epidemiology
Klebsiella Infections microbiology
Klebsiella pneumoniae drug effects
beta-Lactamases metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1560-7917
- Volume :
- 25
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
- Publication Type :
- Academic Journal
- Accession number :
- 32070467
- Full Text :
- https://doi.org/10.2807/1560-7917.ES.2020.25.6.2000085