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Rhizopus Infection in a Preterm Infant: A Novel Use of Posaconazole.

Authors :
Fatemizadeh R
Rodman E
Demmler-Harrison GJ
Dinu D
Source :
The Pediatric infectious disease journal [Pediatr Infect Dis J] 2020 Apr; Vol. 39 (4), pp. 310-312.
Publication Year :
2020

Abstract

Posaconazole is a triazole antifungal with activity against Rhizopus, but data on its use and pharmacokinetics in preterm infants are scarce. In this case, a 24 4/7-week neonate's Rhizopus infection is successfully treated with debridement and combination antifungal therapy with amphotericin B, micafungin and enteral posaconazole. This is the first reported posaconazole use in a preterm neonate with Rhizopus.

Details

Language :
English
ISSN :
1532-0987
Volume :
39
Issue :
4
Database :
MEDLINE
Journal :
The Pediatric infectious disease journal
Publication Type :
Academic Journal
Accession number :
32084112
Full Text :
https://doi.org/10.1097/INF.0000000000002554