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Immunotherapy-related adverse effects on 18 F-FDG PET/CT imaging.
- Source :
-
The British journal of radiology [Br J Radiol] 2020 Jul; Vol. 93 (1111), pp. 20190832. Date of Electronic Publication: 2020 Feb 27. - Publication Year :
- 2020
-
Abstract
- <superscript>18</superscript> F-Fluorodeoxyglucose positron emission tomography/CT imaging plays a key role in oncological imaging including in staging, radiotherapy planning, treatment response and recurrence assessment. Immunotherapies represent a major advance in cancer therapy for a number of tumours with resulting survival benefit. However, a wide range of immune related adverse events (irAEs), some of which can be apparent on imaging, have been reported. These involve many organ systems but particularly endocrine, cutaneous and gastrointestinal systems. Early detection of irAEs is essential to aid diagnosis and management of patients and to reduce associated morbidity. In addition, it is important to not mistake treatment related effects for disease.This pictorial review aims to identify common irAEs and changes seen on <superscript>18</superscript> F-fluorodeoxyglucose positron emission tomography/CT.
- Subjects :
- Aged
Aged, 80 and over
B7-H1 Antigen antagonists & inhibitors
CTLA-4 Antigen antagonists & inhibitors
Female
Humans
Immunotherapy, Adoptive adverse effects
Male
Middle Aged
Programmed Cell Death 1 Receptor antagonists & inhibitors
Rituximab adverse effects
Antineoplastic Agents, Immunological adverse effects
Fluorodeoxyglucose F18
Immunotherapy adverse effects
Neoplasms therapy
Positron Emission Tomography Computed Tomography methods
Radiopharmaceuticals
Subjects
Details
- Language :
- English
- ISSN :
- 1748-880X
- Volume :
- 93
- Issue :
- 1111
- Database :
- MEDLINE
- Journal :
- The British journal of radiology
- Publication Type :
- Academic Journal
- Accession number :
- 32105505
- Full Text :
- https://doi.org/10.1259/bjr.20190832