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Reign in the membrane: How common lipids govern mitochondrial function.

Authors :
Funai K
Summers SA
Rutter J
Source :
Current opinion in cell biology [Curr Opin Cell Biol] 2020 Apr; Vol. 63, pp. 162-173. Date of Electronic Publication: 2020 Feb 24.
Publication Year :
2020

Abstract

The lipids that make up biological membranes tend to be the forgotten molecules of cell biology. The paucity of data on these important entities likely reflects the difficulties of studying and understanding their biological roles, rather than revealing a lack of importance. Indeed, the lipid composition of biological membranes has a profound impact on a diverse array of cellular processes. The focus of this review is on the effects of different lipid classes on the function of mitochondria, particularly bioenergetics, in health and disease.<br /> (Copyright © 2020 Elsevier Ltd. All rights reserved.)

Details

Language :
English
ISSN :
1879-0410
Volume :
63
Database :
MEDLINE
Journal :
Current opinion in cell biology
Publication Type :
Academic Journal
Accession number :
32106003
Full Text :
https://doi.org/10.1016/j.ceb.2020.01.006