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Macular Hole-Related Retinal Detachment in Children with Knobloch Syndrome.
- Source :
-
Ophthalmology. Retina [Ophthalmol Retina] 2020 May; Vol. 4 (5), pp. 498-503. Date of Electronic Publication: 2019 Dec 12. - Publication Year :
- 2020
-
Abstract
- Purpose: To describe the findings and the management of macular hole (MH)-related retinal detachment (RD) in children with Knobloch syndrome.<br />Design: Retrospective interventional case series.<br />Participants: Patients with Knobloch syndrome who presented with MH-related RD.<br />Methods: Retrospective chart review of patients with Knobloch syndrome who presented with MH-related RD from January 2012 to December 2018. Interventions included pars plana vitrectomy and silicone oil tamponade with or without scleral buckle, drainage retinotomy, or relaxing retinectomy.<br />Main Outcome Measures: MH characteristics and surgical anatomical outcome.<br />Results: The study included 9 eyes of 5 patients (age range 2 months to 5 years; median age 5.5 months). Presenting symptoms were poor fixation and nystagmus. The fellow eye of 1 patient had RD due to peripheral breaks. The MH was clinically visible in 8 eyes and detected only by OCT in 1 eye. The RD was shallow and extended to the anterior equator in 7 eyes and localized to a punched-out atrophic lesion in 1 eye. Seven eyes underwent surgical repair. At the last follow-up examination (follow-up range 11 to 42 months; mean 24 months, standard deviation 11.8 months), retinal reattachment with MH closure was achieved in 5 eyes along with marked improvement in fixation.<br />Conclusion: Patients with Knobloch syndrome may develop MH-related RD as early as infancy. The condition may be easily overlooked in children but should be suspected in the setting of high myopia, vitreoretinal degeneration, and encephalocele.<br /> (Copyright © 2019 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Child, Preschool
Encephalocele diagnosis
Female
Humans
Infant
Male
Retinal Degeneration diagnosis
Retinal Detachment complications
Retinal Detachment diagnosis
Retinal Detachment surgery
Retrospective Studies
Tomography, Optical Coherence methods
Encephalocele complications
Endotamponade methods
Retinal Degeneration complications
Retinal Detachment congenital
Retinal Detachment etiology
Silicone Oils administration & dosage
Visual Acuity
Vitrectomy methods
Subjects
Details
- Language :
- English
- ISSN :
- 2468-6530
- Volume :
- 4
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Ophthalmology. Retina
- Publication Type :
- Academic Journal
- Accession number :
- 32111543
- Full Text :
- https://doi.org/10.1016/j.oret.2019.12.004