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Functional comparison of paper-based immunoassays based on antibodies and engineered binding proteins.

Authors :
Sung KJ
Jabbour Al Maalouf Y
Johns QR
Miller EA
Sikes HD
Source :
The Analyst [Analyst] 2020 Apr 07; Vol. 145 (7), pp. 2515-2519. Date of Electronic Publication: 2020 Mar 12.
Publication Year :
2020

Abstract

Binding protein scaffolds, such as rcSso7d, have been investigated for use in diagnostic tests; however, the functional performance of rcSso7d has not yet been studied in comparison to antibodies. Here, we assessed the analyte-binding capabilities of rcSso7d and antibodies on cellulose with samples in buffer and 100% human serum.

Details

Language :
English
ISSN :
1364-5528
Volume :
145
Issue :
7
Database :
MEDLINE
Journal :
The Analyst
Publication Type :
Academic Journal
Accession number :
32163071
Full Text :
https://doi.org/10.1039/d0an00299b