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Sarcopenia negatively affects hip structure analysis variables in a group of Lebanese postmenopausal women.

Authors :
Saddik H
Nasr R
Pinti A
Watelain E
Fayad I
Baddoura R
Berro AJ
Al Rassy N
Lespessailles E
Toumi H
El Hage R
Source :
BMC bioinformatics [BMC Bioinformatics] 2020 Mar 11; Vol. 21 (Suppl 2), pp. 86. Date of Electronic Publication: 2020 Mar 11.
Publication Year :
2020

Abstract

Background: The current study's purpose is to compare hip structural analysis variables in a group of postmenopausal women with sarcopenia and another group of postmenopausal women with normal skeletal muscle mass index. To do so, the current study included 8 postmenopausal women (whose ages ranged between 65 and 84 years) with sarcopenia and 60 age-matched controls (with normal skeletal muscle mass index (SMI)). Body composition and bone parameters were evaluated by dual-energy X-ray absorptiometry (DXA).<br />Results: Weight, lean mass, body mass index, femoral neck cross-sectional area (FN CSA), FN section modulus (Z), FN cross sectional moment of inertia (CSMI), intertrochanteric (IT) CSA, IT Z, IT CSMI, IT cortical thickness (CT), femoral shaft (FS) CSA, FS Z and FS CSMI were significantly greater (p < 0.05) in women with normal SMI compared to women with sarcopenia. In the whole population, SMI was positively associated with IT CSA, IT Z, IT CSMI, IT CT, FS CSA, FS Z, FS CSMI, FS CT but negatively correlated to IT buckling ratio (BR) and FS BR.<br />Conclusion: The current study suggests that sarcopenia has a negative effect on hip bone strength indices in postmenopausal women.

Details

Language :
English
ISSN :
1471-2105
Volume :
21
Issue :
Suppl 2
Database :
MEDLINE
Journal :
BMC bioinformatics
Publication Type :
Academic Journal
Accession number :
32164524
Full Text :
https://doi.org/10.1186/s12859-020-3353-9