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High Rates of Obesity at Presentation Persist into Survivorship across Childhood Cancer Types.
- Source :
-
Childhood obesity (Print) [Child Obes] 2020 Jun; Vol. 16 (4), pp. 250-257. Date of Electronic Publication: 2020 Mar 13. - Publication Year :
- 2020
-
Abstract
- Background: Subtypes of pediatric oncology patients and childhood cancer survivors who are overweight or obese have worse prognosis than their healthy-weighted peers. Several studies have examined weight status in either pediatric patients or survivors with acute leukemia, but few have compared these data across various diagnoses. Objectives: We examined BMI from oncology diagnosis or presentation, through treatment, and into survivorship across the most common cancer types seen in pediatric oncology. Methods: Patients were categorized into three oncologic diagnoses: leukemia and lymphoma ( n = 69), neural tumors ( n = 80), and non-neural solid tumors ( n = 80) at yearly intervals over the course of 11 years. To allow for comparisons across age groups, BMI percentiles were calculated with <5th percentile classified as underweight ( n = 11), the 5th-84th percentile classified as a healthy weight ( n = 129), and above the 85th percentile classified as overweight and obese ( n = 87). Results: At presentation, 45.6% of leukemia and lymphoma patients were overweight or obese, and 44.3% of neural tumor patients were overweight or obese. These high obesity rates persisted into survivorship. Compared to the non-neural tumor group, the leukemia and lymphoma group had a significant increase in BMI percentile over time, while the neural tumor group did not. Conclusions: Pediatric patients with leukemia, lymphoma, and neural tumors and who are overweight or obese at presentation continue this trend into survivorship, indicating a need for management of overweight and obesity through lifestyle interventions concurrent with therapy.
Details
- Language :
- English
- ISSN :
- 2153-2176
- Volume :
- 16
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Childhood obesity (Print)
- Publication Type :
- Academic Journal
- Accession number :
- 32176517
- Full Text :
- https://doi.org/10.1089/chi.2019.0180