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Diterpenes with potential treatment of vitiligo from the aerials parts of Euphorbia antiquorum L.
- Source :
-
Fitoterapia [Fitoterapia] 2020 Jul; Vol. 144, pp. 104583. Date of Electronic Publication: 2020 Mar 29. - Publication Year :
- 2020
-
Abstract
- Six new diterpenes Euphonoids A-F including one ingenol (1), three lathyrane (2-5), one ent-abietane (6) and fifteen known derivatives (7-21) were isolated from the aerial parts of Euphorbia antiquorum L. Their structures were elucidated by physical data analysis. Compounds 1, 12, and 16 improve the melanogenesis in B16 cells in vitro.<br />Competing Interests: Declaration of Competing Interest Author's declares that they are no conflict of interest.<br /> (Copyright © 2020. Published by Elsevier B.V.)
- Subjects :
- Animals
Cell Line, Tumor
China
Diterpenes isolation & purification
Melanoma, Experimental drug therapy
Mice
Molecular Structure
Phytochemicals isolation & purification
Phytochemicals pharmacology
Plant Components, Aerial chemistry
Diterpenes pharmacology
Euphorbia chemistry
Melanins analysis
Vitiligo metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1873-6971
- Volume :
- 144
- Database :
- MEDLINE
- Journal :
- Fitoterapia
- Publication Type :
- Academic Journal
- Accession number :
- 32234374
- Full Text :
- https://doi.org/10.1016/j.fitote.2020.104583