Back to Search Start Over

Ultrasensitive ELISA + enhanced by dendritic mesoporous silica nanoparticles.

Authors :
Lei C
Xu C
Nouwens A
Yu C
Source :
Journal of materials chemistry. B [J Mater Chem B] 2016 Aug 07; Vol. 4 (29), pp. 4975-4979. Date of Electronic Publication: 2016 Jul 05.
Publication Year :
2016

Abstract

An ultrasensitive enzyme-linked immunosorbent assay (ELISA <superscript>+</superscript> ) has been developed by using dendritic mesoporous silica nanoparticles (DMSNs) with high horseradish peroxidase (HRP) loading and easily accessible pore channels for signal amplification. A 2000 times enhancement of detection sensitivity compared to a commercial ELISA kit for insulin detection in serum is achieved.

Details

Language :
English
ISSN :
2050-7518
Volume :
4
Issue :
29
Database :
MEDLINE
Journal :
Journal of materials chemistry. B
Publication Type :
Academic Journal
Accession number :
32264024
Full Text :
https://doi.org/10.1039/c6tb01023g