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Grade I meningioma with disseminated bone disease: a rare clinical phenomenon.
- Source :
-
BMJ case reports [BMJ Case Rep] 2020 Apr 06; Vol. 13 (4). Date of Electronic Publication: 2020 Apr 06. - Publication Year :
- 2020
-
Abstract
- Meningioma, the second most common primary tumour of the central nervous system, is classified into three different grades based on their characteristics. Each tumour grade includes different molecular subtype, growth potential, and thus, different prognosis. Grade I meningioma is the most common subtype with a benign course, in which systemic dissemination rarely occurs. We present the case of a 48-year-old male patient with a history of grade I meningioma who was referred 3 years after the initial diagnosis to our centre due to pelvic pain. Computed tomography (CT) images showed new pelvic bone lesions whose histopathological report was compatible with a grade I meningioma. Neither hormonal therapy concomitant with octreotide nor hydroxiurea treatments were effective. Very little is known about this entity's prevalence and treatment when disseminated disease occurs. Thus, we think it is important to increase the positive and negative clinical experiences in this setting.<br />Competing Interests: Competing interests: None declared.<br /> (© BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.)
- Subjects :
- Antineoplastic Agents, Hormonal therapeutic use
Bone Density Conservation Agents therapeutic use
Bone Diseases diagnostic imaging
Disease Progression
Drug Therapy, Combination
Estrogen Antagonists therapeutic use
Fatal Outcome
Humans
Male
Meningioma classification
Meningioma diagnosis
Meningioma therapy
Middle Aged
Neoplasm Grading methods
Octreotide therapeutic use
Pelvis diagnostic imaging
Pelvis pathology
Radiotherapy methods
Tamoxifen therapeutic use
Tomography, X-Ray Computed methods
Zoledronic Acid therapeutic use
Bone Diseases pathology
Meningeal Neoplasms pathology
Meningioma secondary
Pelvic Pain etiology
Subjects
Details
- Language :
- English
- ISSN :
- 1757-790X
- Volume :
- 13
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- BMJ case reports
- Publication Type :
- Academic Journal
- Accession number :
- 32265210
- Full Text :
- https://doi.org/10.1136/bcr-2019-233708