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Interactive Clustered Heat Map Builder: An easy web-based tool for creating sophisticated clustered heat maps.

Authors :
Ryan MC
Stucky M
Wakefield C
Melott JM
Akbani R
Weinstein JN
Broom BM
Source :
F1000Research [F1000Res] 2019 Oct 14; Vol. 8. Date of Electronic Publication: 2019 Oct 14 (Print Publication: 2019).
Publication Year :
2019

Abstract

Clustered heat maps are the most frequently used graphics for visualization and interpretation of genome-scale molecular profiling data in biology.  Construction of a heat map generally requires the assistance of a biostatistician or bioinformatics analyst capable of working in R or a similar programming language to transform the study data, perform hierarchical clustering, and generate the heat map.  Our web-based Interactive Heat Map Builder can be used by investigators with no bioinformatics experience to generate high-caliber, publication quality maps.  Preparation of the data and construction of a heat map is rarely a simple linear process.  Our tool allows a user to move back and forth iteratively through the various stages of map generation to try different options and approaches.  Finally, the heat map the builder creates is available in several forms, including an interactive Next-Generation Clustered Heat Map that can be explored dynamically to investigate the results more fully.<br />Competing Interests: No competing interests were disclosed.<br /> (Copyright: © 2019 Ryan MC et al.)

Details

Language :
English
ISSN :
2046-1402
Volume :
8
Database :
MEDLINE
Journal :
F1000Research
Publication Type :
Academic Journal
Accession number :
32269754
Full Text :
https://doi.org/10.12688/f1000research.20590.1