A simple and effective dansyl acid based "turn-on" fluorescent probe for detecting labile ferrous iron in physiological saline and live cells.

Labile ferrous iron (Fe ²⁺ ) plays important biochemical functions in many physiologically essential processes. It is very important to find an effective method to detect Fe ²⁺ . Herein, a simple and effective Fe ²⁺ fluorescent probe (FeP1) has been constructed via a unique strategy of Fe ²⁺ -induced reducing reaction. As expected, FeP1 exhibited a 'turn-on' fluorescence response toward Fe ²⁺ over various small analytes, with high selectivity and excellent sensitivity (DL = 18 nM) for the detection of Fe ²⁺ in Tris-DMSO (4:1, pH = 7.4, v/v) solution. Moreover, the probe can act in different real samples, such as physiological saline and living cells.
Competing Interests: Declaration of competing interest We declare that we have no financial and personal relationships with other people or organizations that can inappropriately influence our work, there is no professional or other personal interest of any nature or kind in any product, service and/or company that could be construed as influencing the position presented in, or the review of, the manuscript entitled, “A simple and effective dansyl acid based “turn-on” fluorescent probe for detecting labile ferrous iron in physiological saline and live cells”.
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