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[Perioperative Chemotherapies for Patients with Colorectal Liver Metastasis].

Authors :
Okazaki S
Ishikawa T
Uetake H
Source :
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2020 Apr; Vol. 47 (4), pp. 574-577.
Publication Year :
2020

Abstract

Perioperative chemotherapies are expected to improve prognosis of patients with colorectal liver metastasis(CRLM). In patients with a resectable CRLM, the adjuvant chemotherapy with 5-FU/LV effectively prolongs DFS or RFS. In patients with unresectable CRLM, a neoadjuvant chemotherapy with high response rate and high liver resection rate, such as FOLFOX(or CAPOX, SOX)plus bevacizumab, FOLFOX/FOLFIRI plus cetuximab, or FOLFOXIRI plus bevacizumab, could be an optimal regimen for the conversion therapy.

Subjects

Subjects :
Bevacizumab
Combined Modality Therapy
Fluorouracil
Humans
Leucovorin
Organoplatinum Compounds
Oxaliplatin
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Colorectal Neoplasms drug therapy
Liver Neoplasms drug therapy
Liver Neoplasms secondary
Liver Neoplasms surgery

Details

Language :
Japanese
ISSN :
0385-0684
Volume :
47
Issue :
4
Database :
MEDLINE
Journal :
Gan to kagaku ryoho. Cancer & chemotherapy
Publication Type :
Academic Journal
Accession number :
32389954

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Authors Abstract Subjects Details