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Fusion 68Ga-Prostate-Specific Membrane Antigen PET/MRI on Postoperative Surveillance of Juvenile Nasal Angiofibroma.
- Source :
-
Clinical nuclear medicine [Clin Nucl Med] 2020 Jul; Vol. 45 (7), pp. e325-e326. - Publication Year :
- 2020
-
Abstract
- Prostate-specific membrane antigen (PSMA) is expressed universally in juvenile nasopharyngeal angiofibroma (JNA). As contrast enhancement of postoperative scar is common with contrast-enhanced MRI (CEMRI), diagnosis of residual/recurrent JNA remains perplexing. Prostate-specific membrane antigen PET targets only the neovasculature and may aid in resolving this dilemma. Positive contrast enhancement on CEMRI was noted in a patient after 30 years of initial surgery, simulating recurrence. However, there was no abnormal uptake in PSMA scan, which was confirmed by biopsy as postoperative fibrosis. Ga-PSMA PET/MRI fusion may be an easy and novel technique to aid in differentiating residual/recurrent disease from surgical site reparative tissue.
- Subjects :
- Aged
Angiofibroma pathology
Biopsy
Gallium Isotopes
Gallium Radioisotopes
Humans
Male
Multimodal Imaging
Nasopharyngeal Neoplasms pathology
Postoperative Period
Angiofibroma diagnostic imaging
Angiofibroma surgery
Magnetic Resonance Imaging
Membrane Glycoproteins
Nasopharyngeal Neoplasms diagnostic imaging
Nasopharyngeal Neoplasms surgery
Organometallic Compounds
Positron-Emission Tomography
Subjects
Details
- Language :
- English
- ISSN :
- 1536-0229
- Volume :
- 45
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Clinical nuclear medicine
- Publication Type :
- Academic Journal
- Accession number :
- 32404701
- Full Text :
- https://doi.org/10.1097/RLU.0000000000003041