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Catatonia in Patients with Autism Spectrum Disorder.

Catatonia in Patients with Autism Spectrum Disorder.

Authors :
Ghaziuddin N
Andersen L
Ghaziuddin M
Source :
Child and adolescent psychiatric clinics of North America [Child Adolesc Psychiatr Clin N Am] 2020 Jul; Vol. 29 (3), pp. 443-454.
Publication Year :
2020

Abstract

Catatonia was first described by Karl Ludwig Kahlbaum in 1874, occurring in association with other psychiatric and medical disorders. However, in the nineteenth century the disorder was incorrectly classified as a subtype of schizophrenia. This misclassification persisted until the publication of DSM-5 in 2013 when important changes were incorporated. Although the etiology is unknown, disrupted gamma-aminobutyric acid has been proposed as the underlying pathophysiological mechanism. Key symptoms can be identified under 3 clinical domains: motor, speech, and behavioral. Benzodiazepines and electroconvulsive therapy are the only known effective treatments. Timely recognition and treatment have important outcome, and sometimes lifesaving, implications.<br />Competing Interests: Disclosure N. Ghaziuddin: Royalties from book, Use of Electroconvulsive Therapy in Children and Adolescents. Publisher: Oxford University Press, 2013. M. Ghaziuddin and L. Andersen do not have any disclosures.<br /> (Copyright © 2020 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1558-0490
Volume :
29
Issue :
3
Database :
MEDLINE
Journal :
Child and adolescent psychiatric clinics of North America
Publication Type :
Academic Journal
Accession number :
32471594
Full Text :
https://doi.org/10.1016/j.chc.2020.03.001