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Catatonia in Patients with Autism Spectrum Disorder.
Catatonia in Patients with Autism Spectrum Disorder.
- Source :
-
Child and adolescent psychiatric clinics of North America [Child Adolesc Psychiatr Clin N Am] 2020 Jul; Vol. 29 (3), pp. 443-454. - Publication Year :
- 2020
-
Abstract
- Catatonia was first described by Karl Ludwig Kahlbaum in 1874, occurring in association with other psychiatric and medical disorders. However, in the nineteenth century the disorder was incorrectly classified as a subtype of schizophrenia. This misclassification persisted until the publication of DSM-5 in 2013 when important changes were incorporated. Although the etiology is unknown, disrupted gamma-aminobutyric acid has been proposed as the underlying pathophysiological mechanism. Key symptoms can be identified under 3 clinical domains: motor, speech, and behavioral. Benzodiazepines and electroconvulsive therapy are the only known effective treatments. Timely recognition and treatment have important outcome, and sometimes lifesaving, implications.<br />Competing Interests: Disclosure N. Ghaziuddin: Royalties from book, Use of Electroconvulsive Therapy in Children and Adolescents. Publisher: Oxford University Press, 2013. M. Ghaziuddin and L. Andersen do not have any disclosures.<br /> (Copyright © 2020 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1558-0490
- Volume :
- 29
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Child and adolescent psychiatric clinics of North America
- Publication Type :
- Academic Journal
- Accession number :
- 32471594
- Full Text :
- https://doi.org/10.1016/j.chc.2020.03.001