Novel dose escalation to predict treatment with hydroxyurea (NDEPTH): A randomized controlled trial of a dose-prediction equation to determine maximum tolerated dose of hydroxyurea in pediatric sickle cell disease.

Authors :: George A
Dinu B
Estrada N
Minard CG
Hurwitz R
Mahoney DH
Yates AM
Vaughan M
Carmouche A
Airewele G
Kirk SE
Fasipe T
Uwaezuoke P
Ware RE
Source :: American journal of hematology [Am J Hematol] 2020 Sep; Vol. 95 (9), pp. E242-E244. Date of Electronic Publication: 2020 Jul 04.
Publication Year :: 2020

Subjects :: Adolescent
Anemia, Sickle Cell mortality
Child
Female
Humans
Hydroxyurea adverse effects
Male
Anemia, Sickle Cell drug therapy
Hydroxyurea administration & dosage
Maximum Tolerated Dose

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