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Progressive Decline of the Glomerular Filtration Rate in HIV-infected Children Treated With Tenofovir Disoproxil Fumarate-based Regimens in West and Central Africa.

Authors :
Diack A
Yonaba C
Coulibaly A
Ouedraogo S
Penda I
Bukuru H
Folquet M
Tanoh Eboua F
Sylla M
Blanche S
Tejiokem M
Source :
The Pediatric infectious disease journal [Pediatr Infect Dis J] 2020 Aug; Vol. 39 (8), pp. 737-739.
Publication Year :
2020

Abstract

A cross-sectional study of 358 HIV-1-infected children and adolescents living in Sub-Saharan Africa treated with tenofovir disoproxil fumarate-based regimens for a median of 1.5 interquartile range [0.6-3.1 years] showed a loss of glomerular filtration rate estimated to be 0.41 mL/min/1.73 m per month of treatment. In contrast, there was no decrease depending on the duration of the previous antiretroviral treatment.

Details

Language :
English
ISSN :
1532-0987
Volume :
39
Issue :
8
Database :
MEDLINE
Journal :
The Pediatric infectious disease journal
Publication Type :
Academic Journal
Accession number :
32502129
Full Text :
https://doi.org/10.1097/INF.0000000000002733