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Progressive Decline of the Glomerular Filtration Rate in HIV-infected Children Treated With Tenofovir Disoproxil Fumarate-based Regimens in West and Central Africa.
- Source :
-
The Pediatric infectious disease journal [Pediatr Infect Dis J] 2020 Aug; Vol. 39 (8), pp. 737-739. - Publication Year :
- 2020
-
Abstract
- A cross-sectional study of 358 HIV-1-infected children and adolescents living in Sub-Saharan Africa treated with tenofovir disoproxil fumarate-based regimens for a median of 1.5 interquartile range [0.6-3.1 years] showed a loss of glomerular filtration rate estimated to be 0.41 mL/min/1.73 m per month of treatment. In contrast, there was no decrease depending on the duration of the previous antiretroviral treatment.
- Subjects :
- Adolescent
Africa South of the Sahara
Africa, Central
Child
Child, Preschool
Cross-Sectional Studies
Female
HIV-1 drug effects
Humans
Male
Anti-HIV Agents adverse effects
Anti-HIV Agents therapeutic use
Glomerular Filtration Rate drug effects
Tenofovir adverse effects
Tenofovir therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1532-0987
- Volume :
- 39
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- The Pediatric infectious disease journal
- Publication Type :
- Academic Journal
- Accession number :
- 32502129
- Full Text :
- https://doi.org/10.1097/INF.0000000000002733