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Eslicarbazepine for focal epilepsy and acute intermittent porphyria.

Authors :
Herrera-Fortin T
Pana R
Wesolowska E
Bourré-Tessier J
Nguyen DK
Source :
Epileptic disorders : international epilepsy journal with videotape [Epileptic Disord] 2020 Jun 01; Vol. 22 (3), pp. 349-352.
Publication Year :
2020

Abstract

Porphyrias are rare genetic disorders which cause a deficiency in the enzymes involved in the biosynthesis of heme. The treatment of epilepsy in patients with acute intermittent porphyria can be difficult since many anticonvulsants can increase heme synthesis and trigger porphyric attacks. We report a patient with focal epilepsy successfully treated with eslicarbazepine without exacerbation of porphyria.

Details

Language :
English
ISSN :
1950-6945
Volume :
22
Issue :
3
Database :
MEDLINE
Journal :
Epileptic disorders : international epilepsy journal with videotape
Publication Type :
Academic Journal
Accession number :
32554360
Full Text :
https://doi.org/10.1684/epd.2020.1171