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COVID-19: therapeutic approaches description and discussion.
- Source :
-
Anais da Academia Brasileira de Ciencias [An Acad Bras Cienc] 2020 Jun 15; Vol. 92 (2), pp. e20200466. Date of Electronic Publication: 2020 Jun 15 (Print Publication: 2020). - Publication Year :
- 2020
-
Abstract
- COVID-19 emerged in December 2019 in China, and since then, has disrupted global public health and changed economic paradigms. In dealing with the new Coronavirus, SARS-CoV-2, the world has not faced such extreme global fragility since the "Spanish flu" pandemic in 1918. Researchers globally are dedicating efforts to the search for an effective treatment for COVID-19. Drugs already used in a clinical setting for other pathologies have been tested as a new therapeutic approach against SARS-CoV-2, setting off a frenzy over the preliminary data of different studies. This work aims to compile and discuss the data published thus far. Despite the potential effects of some antivirals and antiparasitic against COVID-19, clinical studies must confirm real effectiveness. However, non-pharmacological approaches have proven to be the most efficient strategy to date.
- Subjects :
- Anti-Bacterial Agents chemistry
Anti-Bacterial Agents pharmacology
Antiparasitic Agents chemistry
Antiparasitic Agents pharmacology
Antiviral Agents chemistry
Antiviral Agents pharmacology
COVID-19
Humans
Macrolides chemistry
Macrolides pharmacology
Pandemics
SARS-CoV-2
Serine Proteinase Inhibitors chemistry
Serine Proteinase Inhibitors pharmacology
Anti-Bacterial Agents administration & dosage
Antiparasitic Agents administration & dosage
Antiviral Agents administration & dosage
Betacoronavirus drug effects
Coronavirus Infections drug therapy
Macrolides administration & dosage
Pneumonia, Viral drug therapy
Serine Proteinase Inhibitors administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1678-2690
- Volume :
- 92
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Anais da Academia Brasileira de Ciencias
- Publication Type :
- Academic Journal
- Accession number :
- 32556054
- Full Text :
- https://doi.org/10.1590/0001-3765202020200466