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Contributions and achievements on schistosomiasis control and elimination in China by NIPD-CTDR.
- Source :
-
Advances in parasitology [Adv Parasitol] 2020; Vol. 110, pp. 1-62. Date of Electronic Publication: 2020 Jun 10. - Publication Year :
- 2020
-
Abstract
- Being a zoonotic parasitic disease, schistosomiasis was widely spread in 12 provinces of Southern China in the 1950s, severly harming human health and hindering economic development. The National Institute of Parasitic Diseases at the Chinese Center for Diseases Control and Prevention, and Chinese Center for Tropical Diseases Research (NIPD-CTDR), as the only professional institution focussing on parasitic diseases at the national level, has played an important role in schistosomiasis control in the country. In this article, we look back at the changes of schistosomiasis endemicity and the contribution of NIPD-CTDR to the national schistosomiasis control programme. We review NIPD-CTDR's activities, including field investigations, design of control strategies and measures, development of diagnostics and drugs, surveillance-response of endemic situation, and monitoring & evaluation of the programme. The NIPD-CTDR has mastered the transmission status of schistosomiasis, mapped the snail distribution, and explored strategies and measures suitable for different types of endemic areas in China. With a good understanding of the life cycle of Schistosoma japonicum and transmission patterns of the disease, advanced research carried out in the NIPD-CTDR based on genomics and modern technology has made it possible to explore highly efficient and soft therapeutic drugs and molluscicides, making it possible to develop new diagnostic tools and produce vaccine candidates. In the field, epidemiological studies, updated strategies and targeted intervention measures developed by scientists from the NIPD-CTDR have contributed significantly to the national schistosomiasis control programme. This all adds up to a strong foundation for eliminating schistosomiasis in China in the near future, and recommendations have been put forward how to reach this goal.<br /> (© 2020 Elsevier Ltd. All rights reserved.)
- Subjects :
- Animals
Cattle
China epidemiology
Disease Eradication
Drug Development
Humans
Molluscacides
Vaccination
Academies and Institutes
Endemic Diseases prevention & control
Government Programs
National Health Programs
Schistosomiasis japonica drug therapy
Schistosomiasis japonica epidemiology
Schistosomiasis japonica transmission
Subjects
Details
- Language :
- English
- ISSN :
- 2163-6079
- Volume :
- 110
- Database :
- MEDLINE
- Journal :
- Advances in parasitology
- Publication Type :
- Academic Journal
- Accession number :
- 32563322
- Full Text :
- https://doi.org/10.1016/bs.apar.2020.04.002