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Potential role of ovomucin and its peptides in modulation of intestinal health: A review.
- Source :
-
International journal of biological macromolecules [Int J Biol Macromol] 2020 Nov 01; Vol. 162, pp. 385-393. Date of Electronic Publication: 2020 Jun 20. - Publication Year :
- 2020
-
Abstract
- Intestinal dysfunction, which may cause a series of metabolic diseases, has become a worldwide health problem. In the past few years, studies have shown that consumption of poultry eggs has the potential to prevent a variety of metabolic diseases, and increasing attention has been directed to the bioactive proteins and their peptides in poultry eggs. This review mainly focused on the biological activities of an important egg-derived protein named ovomucin. Ovomucin and its derivatives have good anti-inflammatory, antioxidant, immunity-regulating and other biological functions. These activities may affect the physical, biological and immune barriers associated with intestinal health. This paper reviewed the structure and the structure-activity relationship of ovomucin,the potential role of ovomucin and its derivatives in modulation of intestinal health are also summarized. Finally, the potential applications of ovomucin and its peptides as functional food components to prevent and assist in the pretreatment of intestinal health problems are prospected.<br />Competing Interests: Declaration of competing interest The authors have declared that there is no conflict of interest.<br /> (Copyright © 2020 Elsevier B.V. All rights reserved.)
- Subjects :
- Animals
Anti-Bacterial Agents metabolism
Anti-Bacterial Agents pharmacology
Anti-Inflammatory Agents pharmacology
Antineoplastic Agents metabolism
Antineoplastic Agents pharmacology
Antioxidants pharmacology
Eggs
Intestinal Mucosa immunology
N-Acetylneuraminic Acid metabolism
Ovomucin chemistry
Ovomucin immunology
Peptides chemistry
Peptides metabolism
Poultry
Structure-Activity Relationship
Anti-Inflammatory Agents metabolism
Antioxidants metabolism
Chickens metabolism
Egg Proteins metabolism
Gastrointestinal Microbiome
Intestinal Mucosa metabolism
Ovomucin metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1879-0003
- Volume :
- 162
- Database :
- MEDLINE
- Journal :
- International journal of biological macromolecules
- Publication Type :
- Academic Journal
- Accession number :
- 32569696
- Full Text :
- https://doi.org/10.1016/j.ijbiomac.2020.06.148