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Meeting report: 2nd workshop of the peptide ADME discussion group.
- Source :
-
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 Jan; Vol. 51 (1), pp. 1-4. Date of Electronic Publication: 2020 Jun 29. - Publication Year :
- 2021
-
Abstract
- Challenges and opportunities within peptide ADME (absorption, distribution, metabolism and elimination) were presented and discussed at the 2nd workshop of the Peptide ADME Discussion Group in Cambridge, UK (17th of September 2019). This article summarises the presentations and discussions from this workshop. The following topics were covered: Peptide drug-drug interactions (DDIs) Regulatory perspectives on peptide ADME studies Bioavailability of therapeutic peptides impacted by metabolism and oligomerization in the subcutaneous compartment Regulated bioanalysis of parent peptide and active metabolites by immunoaffinity LC-MS/MS Peptide radiopharmaceutical development.
Details
- Language :
- English
- ISSN :
- 1366-5928
- Volume :
- 51
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Xenobiotica; the fate of foreign compounds in biological systems
- Publication Type :
- Academic Journal
- Accession number :
- 32571130
- Full Text :
- https://doi.org/10.1080/00498254.2020.1784496