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Circumscribed choroidal haemangioma: Indocyanine green angiography features on scanning laser ophthalmoscopy versus traditional digital fundus photography.

Authors :
Roelofs KA
Sia DIT
O'Day R
Hay G
Arora AK
Cohen VML
Sagoo MS
Source :
Eye (London, England) [Eye (Lond)] 2021 Apr; Vol. 35 (4), pp. 1178-1186. Date of Electronic Publication: 2020 Jun 25.
Publication Year :
2021

Abstract

Background and Objective: Circumscribed choroidal haemangioma (CCH) has several characteristic clinical and angiographic features. We aimed to compare indocyanine green angiography (ICG) findings of CCH captured on a traditional digital camera system (DCS) to newer scanning laser ophthalmoscopy (SLO) platforms.<br />Study Design/materials and Methods: A total of 35 patients over a 10-year period diagnosed with CCH using ICG were included (18 imaged with DCS and 17 with SLO).<br />Results: On early ICG frames, intrinsic vessels were apparent in two-thirds (12/18; 67%) of the DCS group compared with all of eyes in the SLO group (p = 0.020). In addition, at maximal hyperfluorescence, most eyes imaged with DCS had a feathery appearance (16/18; 89%) compared with those in the SLO group which all (17/17; 100%) displayed a granular appearance (p < 0.001). The presence of hot spots at maximal hyperfluorescence was also more common in the SLO group (12/17; 71%) versus the DCS group (0/18; 0%) (p < 0.001). Finally, intrinsic vessels and vascular loops could be identified throughout the entire duration of the ICG in 100% of the SLO cases (17/17) versus only 11% (2/18) of DCS cases (p < 0.001).<br />Conclusions: The visualization of intrinsic vessels, vascular loops, and "hot spots" in CCH is significantly enhanced with SLO compared with DCS. Many characteristic mid-late angiographic findings of CCH are more optimally visualized on SLO which may negate the need for late frames (>30 min) without compromising diagnostic accuracy.

Details

Language :
English
ISSN :
1476-5454
Volume :
35
Issue :
4
Database :
MEDLINE
Journal :
Eye (London, England)
Publication Type :
Academic Journal
Accession number :
32587385
Full Text :
https://doi.org/10.1038/s41433-020-1044-4