Increased expression of dermal LL37 may trigger migration of CCR7+ regulatory T cells in extramammary Paget's disease.

Authors :: Lyu C
Fujimura T
Amagai R
Ohuchi K
Sato Y
Tanita K
Matsushita S
Fujisawa Y
Otsuka A
Yamamoto Y
Takahashi T
Aiba S
Source :: Journal of dermatological science [J Dermatol Sci] 2020 Jul; Vol. 99 (1), pp. 65-68. Date of Electronic Publication: 2020 May 17.
Publication Year :: 2020
Abstract: Competing Interests: Declaration of Competing Interest The authors have no conflict of interest to declare.

Subjects :: Aged
Aged, 80 and over
Cell Movement immunology
Female
Humans
Male
Middle Aged
Neoplasm Invasiveness immunology
Paget Disease, Extramammary pathology
Receptors, CCR7 metabolism
Skin Neoplasms pathology
T-Lymphocytes, Regulatory metabolism
Tumor Microenvironment immunology
Cathelicidins
Antimicrobial Cationic Peptides metabolism
Paget Disease, Extramammary immunology
Skin pathology
Skin Neoplasms immunology
T-Lymphocytes, Regulatory immunology

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