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The bacteriology of recurrent acute exacerbations of chronic rhinosinusitis: a longitudinal analysis.
- Source :
-
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery [Eur Arch Otorhinolaryngol] 2020 Nov; Vol. 277 (11), pp. 3051-3057. Date of Electronic Publication: 2020 Jul 04. - Publication Year :
- 2020
-
Abstract
- Purpose: The purpose of this study was to describe the microbiology of recurrent acute exacerbations of chronic rhinosinusitis over time.<br />Methods: Retrospective review of patients with recurrent acute exacerbations of chronic rhinosinusitis who underwent endoscopic-guided cultures during acute exacerbations of chronic rhinosinusitis.<br />Results: 386 cultures were obtained from 112 patients during recurrent acute exacerbations of CRS. A change of bacterial isolates during the course of recurrent exacerbations was observed in 68% (76/112) of patients, necessitating a change of treatment in 40% (45/112). The main risk factor for the subsequent change in cultures was polymicrobial growth. Sinus surgery was not associated with subsequent change in cultured isolates. Resistant strains developed in 11.6% (13/112) of patients, of whom those with abnormal mucociliary clearance being at the highest risk.<br />Conclusion: Repeated middle meatal cultures should be considered in patients with recurrent exacerbations of CRS, particularly in cases not responding to standard therapy.
- Subjects :
- Chronic Disease
Endoscopy
Humans
Retrospective Studies
Bacteriology
Rhinitis
Sinusitis
Subjects
Details
- Language :
- English
- ISSN :
- 1434-4726
- Volume :
- 277
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
- Publication Type :
- Academic Journal
- Accession number :
- 32623506
- Full Text :
- https://doi.org/10.1007/s00405-020-06157-7