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Salivary gland hyalinizing clear-cell carcinoma with cutaneous metastasis: A rare and deceptive tumor.

Authors :
Shaar RA
Zia S
Alhamar M
Romano T
Shaw B
Keller C
Friedman BJ
Source :
Journal of cutaneous pathology [J Cutan Pathol] 2021 Jan; Vol. 48 (1), pp. 86-89. Date of Electronic Publication: 2020 Sep 14.
Publication Year :
2021

Abstract

Clear-cell carcinoma (CCC) is an uncommon malignant tumor of minor salivary glands. It characteristically has a low-grade morphology and a favorable outcome by most reports. An EWSR1-ATF1 fusion can be detected in the majority of cases. We present a rare case of CCC, which had an aggressive course with the development of cutaneous metastases. Practicing dermatopathologists should be aware of this tumor given its low-grade appearance and histopathologic resemblance to other primary cutaneous adnexal and metastatic neoplasms.<br /> (© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

Details

Language :
English
ISSN :
1600-0560
Volume :
48
Issue :
1
Database :
MEDLINE
Journal :
Journal of cutaneous pathology
Publication Type :
Report
Accession number :
32640078
Full Text :
https://doi.org/10.1111/cup.13799