Pharmacokinetic analysis of (6S)-5-formyltetrahydrofolate (1-CF), (6R)-5-formyltetrahydrofolate (d-CF) and 5-methyltetrahydrofolate (5-CH3-THF) in patients receiving constant i.v. infusion of high-dose (6R,S)-5-formyltetrahydrofolate (leucovorin).

Authors :: Straw JA
Newman EM
Source :: Advances in experimental medicine and biology [Adv Exp Med Biol] 1988; Vol. 244, pp. 53-8.
Publication Year :: 1988

Subjects :: Drug Administration Schedule
Drug Evaluation
Fluorouracil administration & dosage
Humans
Infusions, Intravenous
Leucovorin administration & dosage
Neoplasms blood
Neoplasms drug therapy
Neoplasms urine
Stereoisomerism
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Leucovorin pharmacokinetics
Tetrahydrofolates pharmacokinetics

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