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Phyto-fabricated Cr 2 O 3 nanoparticle for multifunctional biomedical applications.
- Source :
-
Nanomedicine (London, England) [Nanomedicine (Lond)] 2020 Jul; Vol. 15 (17), pp. 1653-1669. Date of Electronic Publication: 2020 Jul 16. - Publication Year :
- 2020
-
Abstract
- Aim: The biosynthesis of chromium oxide nanoparticles (Cr <subscript>2</subscript> O <subscript>3</subscript> NPs), using Hyphaene thebaica as a bioreductant, for assessment of their potential nanomedicinal applications. Materials & methods: Biosynthesized Cr <subscript>2</subscript> O <subscript>3</subscript> NPs were characterized by x-ray diffraction, Fourier-transform infrared spectroscopy, energy dispersive x-ray spectroscopy, scanning and transmission electron microscopy, selected area electron diffraction, UV-Vis spectroscopy and ΞΆ-potential measurement. In vitro assays were used to assess the biological properties of Cr <subscript>2</subscript> O <subscript>3</subscript> NPs. Results: Nanoparticles with size approximately 25-38 nm were obtained with a characteristic Cr-O vibration at 417 cm <superscript>-1</superscript> . A broad spectrum antimicrobial potential and antioxidant nature is reported. Slight inhibition of polio virus and biocompatibility at low doses was observed. Conclusion: We conclude a multifunctional nature of biogenic Cr <subscript>2</subscript> O <subscript>3</subscript> NPs.
Details
- Language :
- English
- ISSN :
- 1748-6963
- Volume :
- 15
- Issue :
- 17
- Database :
- MEDLINE
- Journal :
- Nanomedicine (London, England)
- Publication Type :
- Academic Journal
- Accession number :
- 32669064
- Full Text :
- https://doi.org/10.2217/nnm-2020-0129