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Early myocardial injury biomarkers in diabetic hyperlipidemic rats: Impact of 10-dehydrogingerdione and vitamin D3.
- Source :
-
Experimental biology and medicine (Maywood, N.J.) [Exp Biol Med (Maywood)] 2020 Sep; Vol. 245 (15), pp. 1326-1334. Date of Electronic Publication: 2020 Jul 19. - Publication Year :
- 2020
-
Abstract
- Impact Statement: Hyperlipidemia represents a major risk factor for cardiovascular diseases leading to myocardial injury (MI). The present study aimed to illustrate the pattern of myocardial injury induced in diabetic hyperlipidemic rat model and the effect of vitamin D3, 10-dehydrogingerdione (10-DHGD) intake either individually or in combination form.
- Subjects :
- Animals
Aorta pathology
Blood Glucose metabolism
Diabetes Mellitus, Experimental genetics
Fatty Acid Binding Protein 3 metabolism
Glycated Hemoglobin metabolism
Glycopeptides metabolism
Guaiacol pharmacology
Lipids blood
Male
RNA, Messenger genetics
RNA, Messenger metabolism
Rats, Wistar
Biomarkers blood
Cholecalciferol pharmacology
Diabetes Mellitus, Experimental blood
Diabetes Mellitus, Experimental pathology
Guaiacol analogs & derivatives
Hyperlipidemias blood
Hyperlipidemias pathology
Myocardium pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1535-3699
- Volume :
- 245
- Issue :
- 15
- Database :
- MEDLINE
- Journal :
- Experimental biology and medicine (Maywood, N.J.)
- Publication Type :
- Academic Journal
- Accession number :
- 32686474
- Full Text :
- https://doi.org/10.1177/1535370220943124