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Clinical outcomes of microdissection testicular sperm extraction-intracytoplasmic sperm injection with fresh or cryopreserved sperm in patients with nonobstructive azoospermia.
- Source :
-
Asian journal of andrology [Asian J Androl] 2021 Mar-Apr; Vol. 23 (2), pp. 211-214. - Publication Year :
- 2021
-
Abstract
- We performed this study to evaluate the clinical outcomes of microdissection testicular sperm extraction-intracytoplasmic sperm injection (micro-TESE-ICSI) treatment that used fresh or cryopreserved sperm in patients with nonobstructive azoospermia (NOA). A total of 338 NOA patients with 344 consecutive cycles received treatment in the reproductive medicine center of Peking University Third Hospital in Beijing, China, from January 2014 to December 2017. Fresh oocytes and fresh sperm were used in 222 patients with 234 cycles (Group A). Fresh oocytes and cryopreserved sperm were used in 116 patients with 110 cycles (Group B). We compared patient characteristics, embryonic development, and pregnancy outcomes between Groups A and B. There was no statistical difference in the patient characteristics, and no differences were observed with fertilization or quality embryo rates between Groups A and B. The rates of clinical pregnancy and live birth were both higher for Group A than those for Group B (both P < 0.05). In conclusion, fresh testicular sperm appears to produce better ICSI outcomes than cryopreserved testicular sperm in patients with NOA.<br />Competing Interests: None
- Subjects :
- Adult
Embryo Implantation
Embryo Transfer
Embryo, Mammalian
Female
Humans
Male
Microdissection
Pregnancy
Pregnancy Outcome
Pregnancy Rate
Retrospective Studies
Testis
Treatment Outcome
Young Adult
Azoospermia therapy
Cryopreservation
Semen Preservation
Sperm Injections, Intracytoplasmic methods
Sperm Retrieval
Subjects
Details
- Language :
- English
- ISSN :
- 1745-7262
- Volume :
- 23
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Asian journal of andrology
- Publication Type :
- Academic Journal
- Accession number :
- 32719193
- Full Text :
- https://doi.org/10.4103/aja.aja_38_20