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'The Double-Edged Sword' - An hypothesis for Covid-19-induced salivary biomarkers.
- Source :
-
Medical hypotheses [Med Hypotheses] 2020 Oct; Vol. 143, pp. 110124. Date of Electronic Publication: 2020 Jul 21. - Publication Year :
- 2020
-
Abstract
- Utilising biomarkers for COVID-19 diagnosis, prediction of treatment response and overall prognostication have been investigated recently. However, these ventures have only considered the use of blood-based molecular markers. Saliva is another biofluid that warrants being applied in similar fashion with major advantages that centres on its non-invasive and repeatable collection as well as cost-efficiency. To this end, this article presents a hypothesis for the sources of biomarkers useful clinically for COVID-19 disease outcome estimation and identify the likely implications of their detection in saliva.<br />Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (Copyright © 2020 Elsevier Ltd. All rights reserved.)
- Subjects :
- Biomarkers blood
COVID-19
Coronavirus Infections diagnosis
Coronavirus Infections immunology
Coronavirus Infections therapy
Cytokines analysis
Diagnostic Tests, Routine
Extracellular Vesicles
Gingival Crevicular Fluid chemistry
Humans
MicroRNAs analysis
Mouth Diseases complications
Mouth Diseases metabolism
Pneumonia, Viral diagnosis
Pneumonia, Viral immunology
Pneumonia, Viral therapy
SARS-CoV-2
Saliva immunology
Saliva virology
Salivary Glands metabolism
Salivary Glands virology
Salivary Proteins and Peptides analysis
Betacoronavirus
Biomarkers analysis
Coronavirus Infections metabolism
Models, Immunological
Pandemics
Pneumonia, Viral metabolism
Saliva chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1532-2777
- Volume :
- 143
- Database :
- MEDLINE
- Journal :
- Medical hypotheses
- Publication Type :
- Academic Journal
- Accession number :
- 32721813
- Full Text :
- https://doi.org/10.1016/j.mehy.2020.110124