Back to Search Start Over

Coronavirus Disease 2019 (COVID-19): A Haematologist's Perspective.

Authors :
Cheung CKM
Law MF
Lui GCY
Wong SH
Wong RSM
Source :
Acta haematologica [Acta Haematol] 2021; Vol. 144 (1), pp. 10-23. Date of Electronic Publication: 2020 Jul 28.
Publication Year :
2021

Abstract

Coronavirus disease 2019 (COVID-19) is affecting millions of patients worldwide. It is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which belongs to the family Coronaviridae, with 80% genomic similarities to SARS-CoV. Lymphopenia was commonly seen in infected patients and has a correlation to disease severity. Thrombocytopenia, coagulation abnormalities, and disseminated intravascular coagulation were observed in COVID-19 patients, especially those with critical illness and non-survivors. This pandemic has caused disruption in communities and hospital services, as well as straining blood product supply, affecting chemotherapy treatment and haematopoietic stem cell transplantation schedule. In this article, we review the haematological manifestations of the disease and its implication on the management of patients with haematological disorders.<br /> (© 2020 S. Karger AG, Basel.)

Details

Language :
English
ISSN :
1421-9662
Volume :
144
Issue :
1
Database :
MEDLINE
Journal :
Acta haematologica
Publication Type :
Academic Journal
Accession number :
32721958
Full Text :
https://doi.org/10.1159/000510178