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CRISPR/Cas: a potential gene-editing tool in the nervous system.

Authors :
Gao Y
Gao K
Yang H
Source :
Cell regeneration (London, England) [Cell Regen] 2020 Aug 06; Vol. 9 (1), pp. 12. Date of Electronic Publication: 2020 Aug 06.
Publication Year :
2020

Abstract

The rapidly developmental RNA-guided CRISPR/Cas system is a powerful tool for RNA and DNA editing in a variety of cells from different species and makes a great contribution to gene function research, disease model generation and gene therapy development in the past few years. The ease of use, low cost and high efficiency of CRISPR/Cas make it commonly used in various conditions. In this review, we introduce the CRISPR/Cas system and its diverse applications in nervous system briefly, which provides a better understanding for its potential application values.

Details

Language :
English
ISSN :
2045-9769
Volume :
9
Issue :
1
Database :
MEDLINE
Journal :
Cell regeneration (London, England)
Publication Type :
Academic Journal
Accession number :
32761306
Full Text :
https://doi.org/10.1186/s13619-020-00044-6