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Black esophagus: a syndrome of acute esophageal necrosis associated with active alcohol drinking.
- Source :
-
BMJ open gastroenterology [BMJ Open Gastroenterol] 2020 Aug; Vol. 7 (1). - Publication Year :
- 2020
-
Abstract
- Black esophagus, also known as acute esophageal necrosis (AEN) syndrome, is a rare entity characterized by patchy or diffuse circumferential black pigmentation of the esophageal mucosa from ischemic necrosis. It may present with life-threatening upper gastrointestinal hemorrhage resulting in high mortality in immunocompromised patients. Advanced age with multiple comorbidities compounded with compromised hemodynamic states are poor prognostic factors. Findings on laboratory work-up and radiological imaging are non-specific. After initial resuscitation, endoscopic evaluation and histological examination of esophageal biopsy are diagnostic. Early recognition and aggressive resuscitation are the fundamental principles for the management of AEN and better outcome of the disease. We report a case of a 56-year-old woman with diabetes mellitus, gastro-esophageal reflux disease, and active alcohol binging who presented with hematemesis and acute epigastric pain due to AEN. This case illustrates a rare etiology of AEN due to active alcohol drinking, which may be overlooked. Physician awareness about this etiology is important as early recognition and timely management may improve survival.<br />Competing Interests: Competing interests: None declared.<br /> (© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
- Subjects :
- Acute Disease
Adult
Aged
Aged, 80 and over
Awareness
Endoscopy methods
Esophageal Diseases pathology
Esophagus abnormalities
Esophagus blood supply
Female
Gastroesophageal Reflux complications
Gastrointestinal Hemorrhage therapy
Hematemesis diagnosis
Humans
Male
Middle Aged
Proton Pump Inhibitors therapeutic use
Resuscitation methods
Treatment Outcome
Alcohol Drinking adverse effects
Esophageal Diseases etiology
Esophagus pathology
Gastrointestinal Hemorrhage etiology
Hematemesis etiology
Necrosis diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 2054-4774
- Volume :
- 7
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- BMJ open gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 32788199
- Full Text :
- https://doi.org/10.1136/bmjgast-2020-000466