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Hospitalization Rates and Characteristics of Children Aged <18 Years Hospitalized with Laboratory-Confirmed COVID-19 - COVID-NET, 14 States, March 1-July 25, 2020.

Authors :
Kim L
Whitaker M
O'Halloran A
Kambhampati A
Chai SJ
Reingold A
Armistead I
Kawasaki B
Meek J
Yousey-Hindes K
Anderson EJ
Openo KP
Weigel A
Ryan P
Monroe ML
Fox K
Kim S
Lynfield R
Bye E
Shrum Davis S
Smelser C
Barney G
Spina NL
Bennett NM
Felsen CB
Billing LM
Shiltz J
Sutton M
West N
Talbot HK
Schaffner W
Risk I
Price A
Brammer L
Fry AM
Hall AJ
Langley GE
Garg S
Source :
MMWR. Morbidity and mortality weekly report [MMWR Morb Mortal Wkly Rep] 2020 Aug 14; Vol. 69 (32), pp. 1081-1088. Date of Electronic Publication: 2020 Aug 14.
Publication Year :
2020

Abstract

Most reported cases of coronavirus disease 2019 (COVID-19) in children aged &lt;18 years appear to be asymptomatic or mild (1). Less is known about severe COVID-19 illness requiring hospitalization in children. During March 1-July 25, 2020, 576 pediatric COVID-19 cases were reported to the COVID-19-Associated Hospitalization Surveillance Network (COVID-NET), a population-based surveillance system that collects data on laboratory-confirmed COVID-19-associated hospitalizations in 14 states (2,3). Based on these data, the cumulative COVID-19-associated hospitalization rate among children aged &lt;18 years during March 1-July 25, 2020, was 8.0 per 100,000 population, with the highest rate among children aged &lt;2 years (24.8). During March 21-July 25, weekly hospitalization rates steadily increased among children (from 0.1 to 0.4 per 100,000, with a weekly high of 0.7 per 100,000). Overall, Hispanic or Latino (Hispanic) and non-Hispanic black (black) children had higher cumulative rates of COVID-19-associated hospitalizations (16.4 and 10.5 per 100,000, respectively) than did non-Hispanic white (white) children (2.1). Among 208 (36.1%) hospitalized children with complete medical chart reviews, 69 (33.2%) were admitted to an intensive care unit (ICU); 12 of 207 (5.8%) required invasive mechanical ventilation, and one patient died during hospitalization. Although the cumulative rate of pediatric COVID-19-associated hospitalization remains low (8.0 per 100,000 population) compared with that among adults (164.5),* weekly rates increased during the surveillance period, and one in three hospitalized children were admitted to the ICU, similar to the proportion among adults. Continued tracking of SARS-CoV-2 infections among children is important to characterize morbidity and mortality. Reinforcement of prevention efforts is essential in congregate settings that serve children, including childcare centers and schools.&lt;br /&gt;Competing Interests: All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. Evan Anderson reports personal fees from AbbVie, Pfizer and Sanofi Pasteur, and grants from MedImmune, Regeneron, PaxVax, Pfizer, GSK, Merck, Novavax, Sanofi Pasteur, Micron, and Janssen, outside the submitted work. William Schaffner reports personal fees from Pfizer and VBI Vaccines outside the submitted work. No other potential conflicts of interest were disclosed.

Details

Language :
English
ISSN :
1545-861X
Volume :
69
Issue :
32
Database :
MEDLINE
Journal :
MMWR. Morbidity and mortality weekly report
Publication Type :
Academic Journal
Accession number :
32790664
Full Text :
https://doi.org/10.15585/mmwr.mm6932e3