5-aminolevulinic acid photodynamic therapy and excision surgery for nevoid basal cell carcinoma syndrome with multiple basal cell carcinomas and PTCH1 mutation.

Authors :: Li C
Chen P
Li Z
Wang Y
He S
Shi M
Wang Q
Xu M
Li Q
Chen H
Zeng K
Liang J
Zhang X
Source :: Photodiagnosis and photodynamic therapy [Photodiagnosis Photodyn Ther] 2020 Dec; Vol. 32, pp. 101968. Date of Electronic Publication: 2020 Aug 21.
Publication Year :: 2020
Abstract: This report describes a PTCH1 c.1804C > T (p.Arg602*) mutation causing a Chinese nevoid basal cell carcinoma syndrome (NBCCS) with multiple basal cell carcinoma (BCC) phenotype. Multiple modalities including microwave ablation, photodynamic therapy, and excision surgery have a good respond to the NBCCS. The current results broaden the spectrum of PTCH1 mutations responsible for NBCCS.<br /> (Copyright © 2020. Published by Elsevier B.V.)

Subjects :: Aminolevulinic Acid therapeutic use
Hamartoma Syndrome, Multiple
Humans
Mutation
Photosensitizing Agents therapeutic use
Basal Cell Nevus Syndrome drug therapy
Basal Cell Nevus Syndrome genetics
Carcinoma, Basal Cell
Photochemotherapy methods

Full Text Access

Tools