Back to Search
Start Over
Formulations for Allergen Immunotherapy in Human and Veterinary Patients: New Candidates on the Horizon.
- Source :
-
Frontiers in immunology [Front Immunol] 2020 Aug 04; Vol. 11, pp. 1697. Date of Electronic Publication: 2020 Aug 04 (Print Publication: 2020). - Publication Year :
- 2020
-
Abstract
- Allergen immunotherapy is currently the only causal treatment for allergic diseases in human beings and animals. It aims to re-direct the immune system into a tolerogenic or desensitized state. Requirements include clinical efficacy, safety, and schedules optimizing patient or owner compliance. To achieve these goals, specific allergens can be formulated with adjuvants that prolong tissue deposition and support uptake by antigen presenting cells, and/or provide a beneficial immunomodulatory action. Here, we depict adjuvant formulations being investigated for human and veterinary allergen immunotherapy.<br /> (Copyright © 2020 Pali-Schöll, DeBoer, Alessandri, Seida, Mueller and Jensen-Jarolim.)
- Subjects :
- Allergens chemistry
Animals
Drug Compounding veterinary
Humans
Hypersensitivity immunology
Hypersensitivity therapy
Veterinary Drugs chemistry
Adjuvants, Immunologic therapeutic use
Allergens therapeutic use
Desensitization, Immunologic veterinary
Hypersensitivity veterinary
Immune Tolerance
Veterinary Drugs therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1664-3224
- Volume :
- 11
- Database :
- MEDLINE
- Journal :
- Frontiers in immunology
- Publication Type :
- Academic Journal
- Accession number :
- 32849594
- Full Text :
- https://doi.org/10.3389/fimmu.2020.01697