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Relationship status and other demographic influences on survival in patients with ovarian cancer.
- Source :
-
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society [Int J Gynecol Cancer] 2020 Dec; Vol. 30 (12), pp. 1922-1927. Date of Electronic Publication: 2020 Sep 12. - Publication Year :
- 2020
-
Abstract
- Objective: To evaluate the influence of marital status and other demographic factors on survival of patients with ovarian cancer.<br />Study Design: Data were obtained from the Surveillance, Epidemiology, and End Results database from 2010 to 2015. Analyses were performed using Kaplan-Meier and multivariate Cox proportional hazard methods.<br />Results: Of 19 643 patients with ovarian cancer (median age 60 years, range 18-99), 16 278 (83%), 1381 (7%), 1856 (9%), and 128 (1%) were White, Black, Asian, and Native American, respectively. The majority of patients (10 769, 55%) were married while 4155 (21%) were single, 2278 (12%) were divorced, and 2441 (12%) were widowed. Patients were more likely to be married if they were Asian (65%) or White (56%) than if they were Black (31%) or Native American (39%) (p<0.001). Most married patients were insured (n=9760 (91%), non-Medicaid) compared with 3002 (72%) of single, 1777 (78%) divorced, and 2102 (86%) of widowed patients (p<0.001). Married patients were more likely to receive chemotherapy than single, divorced, and widowed patients (8515 (79%) vs 3000 (72%), 1747 (77%), and 1650 (68%), respectively; p<0.001). The 5-year disease-specific survival of the overall group was 58%. Married patients had improved survival of 60% compared with divorced (52%) and widowed (44%) patients (p<0.001). On multivariate analysis, older age (HR 1.02, 95% CI 1.016 to 1.021, p<0.001), Black race (HR 1.24, 95% CI 1.11 to 1.38, p<0.001), and Medicaid (HR 1.19, 95% CI 1.09 to 1.30, p<0.001) or uninsured status (HR 1.23, 95% CI 1.05 to 1.44, p<0.01) carried a worse prognosis. Single (HR 1.17, 95% CI 1.08 to 1.26, p<0.001), divorced (HR 1.14, 95% CI 1.04 to 1.25, p<0.01), and widowed (HR 1.16, 95% CI 1.06 to 1.26, p<0.001) patients had decreased survival.<br />Conclusion: Married patients with ovarian cancer were more likely to undergo chemotherapy with better survival rates. Black, uninsured, or patients with Medicaid insurance had poorer outcomes.<br />Competing Interests: Competing interests: None declared.<br /> (© IGCS and ESGO 2020. No commercial re-use. See rights and permissions. Published by BMJ.)
- Subjects :
- Adolescent
Adult
Black or African American statistics & numerical data
Aged
Aged, 80 and over
Asian statistics & numerical data
Female
Humans
Kaplan-Meier Estimate
Marital Status
Middle Aged
Ovarian Neoplasms ethnology
Ovarian Neoplasms psychology
Proportional Hazards Models
SEER Program
Socioeconomic Factors
United States epidemiology
White People statistics & numerical data
Young Adult
American Indian or Alaska Native statistics & numerical data
Ovarian Neoplasms mortality
Subjects
Details
- Language :
- English
- ISSN :
- 1525-1438
- Volume :
- 30
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
- Publication Type :
- Academic Journal
- Accession number :
- 32920535
- Full Text :
- https://doi.org/10.1136/ijgc-2020-001512