Ghrelin and vascular protection.

Authors :: Pearson JT
Shirai M
Sukumaran V
Du CK
Tsuchimochi H
Sonobe T
Waddingham MT
Katare R
Schwenke DO
Source :: Vascular biology (Bristol, England) [Vasc Biol] 2019 Sep 05; Vol. 1 (1), pp. H97-H102. Date of Electronic Publication: 2019 Sep 05 (Print Publication: 2019).
Publication Year :: 2019
Abstract: Ghrelin is a small peptide with important roles in the regulation of appetite, gut motility, glucose homeostasis as well as cardiovascular protection. This review highlights the role that acyl ghrelin plays in maintaining normal endothelial function by maintaining the balance of vasodilator-vasoconstrictor factors, inhibiting inflammatory cytokine production and immune cell recruitment to sites of vascular injury and by promoting angiogenesis.<br />Competing Interests: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of this review.<br /> (© 2019 The authors.)