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Mesalazine-induced lung injury with severe respiratory failure successfully treated with steroids and non-invasive positive pressure ventilation.
- Source :
-
Respiratory medicine case reports [Respir Med Case Rep] 2020 Aug 03; Vol. 31, pp. 101157. Date of Electronic Publication: 2020 Aug 03 (Print Publication: 2020). - Publication Year :
- 2020
-
Abstract
- Drug-induced lung injury (DLI) has become more common because of the increasing number of therapeutic agents in use. Mesalazine, also known as 5-aminosalicylic acid (5-ASA), is one of the key drugs for the treatment of ulcerative colitis (UC). Although mesalazine-induced lung injury has been previously reported, few cases have included severe respiratory failure. In this report, we present a case of mesalazine-induced lung injury with severe respiratory failure, which was improved by discontinuation of mesalazine and introduction of corticosteroid therapy and ventilation support with non-invasive positive pressure ventilation (NPPV). We also review the previous literature on mesalazine-induced lung injury.<br /> (© 2020 The Author(s).)
Details
- Language :
- English
- ISSN :
- 2213-0071
- Volume :
- 31
- Database :
- MEDLINE
- Journal :
- Respiratory medicine case reports
- Publication Type :
- Report
- Accession number :
- 32953447
- Full Text :
- https://doi.org/10.1016/j.rmcr.2020.101157