Back to Search
Start Over
Expression of Arginine Vasopressin Type 2 Receptor in Canine Mammary Tumours: Preliminary Results.
- Source :
-
Journal of comparative pathology [J Comp Pathol] 2020 Aug; Vol. 179, pp. 36-40. Date of Electronic Publication: 2020 Aug 14. - Publication Year :
- 2020
-
Abstract
- The aims of this study were to investigate the potential association of arginine vasopressin type 2 receptor (AVPR2) in canine mammary tumours with expression of oestrogen receptors α (ORα) and β (ORβ) and clinicopathological features of the neoplasms. Twenty-six canine mammary tumour samples (11 benign, 15 malignant) were immunolabelled for AVPR2, ORα and ORβ antigens. Moderate to intense immunolabelling of AVPR2 antigen, found in all neoplasms, was not significantly associated with expression of ORα or ORβ antigens or with clinicopathological features. These findings indicate a potential role for AVPR2 in the development of canine mammary tumours and the use of AVPR2-selective vasopressin analogues as therapeutic options.<br /> (Copyright © 2020 Elsevier Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1532-3129
- Volume :
- 179
- Database :
- MEDLINE
- Journal :
- Journal of comparative pathology
- Publication Type :
- Academic Journal
- Accession number :
- 32958145
- Full Text :
- https://doi.org/10.1016/j.jcpa.2020.07.005