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Can Microbes Boost Tregs to Suppress Food Sensitivities?

Authors :
Siller M
Zeng Y
Hinterleitner R
Source :
Trends in immunology [Trends Immunol] 2020 Nov; Vol. 41 (11), pp. 967-971. Date of Electronic Publication: 2020 Oct 06.
Publication Year :
2020

Abstract

Food sensitivities are on the rise worldwide. Peripheral induced regulatory T cells (pTreg cells) play a central role in oral tolerance to dietary antigens and can contribute to preventing the onset of immune-mediated food sensitivities. Here, we discuss the potential of microbial-derived products in promoting pTreg cell proliferation for re-establishing oral tolerance in immune-mediated food sensitivities.<br /> (Copyright © 2020 Elsevier Ltd. All rights reserved.)

Subjects

Subjects :
Cell Proliferation
Food Hypersensitivity prevention & control
Humans
Immune Tolerance immunology
Diet
Food Hypersensitivity immunology
Food Hypersensitivity microbiology
T-Lymphocytes, Regulatory cytology
T-Lymphocytes, Regulatory immunology

Details

Language :
English
ISSN :
1471-4981
Volume :
41
Issue :
11
Database :
MEDLINE
Journal :
Trends in immunology
Publication Type :
Academic Journal
Accession number :
33036909
Full Text :
https://doi.org/10.1016/j.it.2020.09.005
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