Toxin-Induced Channelopathies, Neuromuscular Junction Disorders, and Myopathy.

Authors :: Janecek J
Kushlaf H
Source :: Neurologic clinics [Neurol Clin] 2020 Nov; Vol. 38 (4), pp. 765-780. Date of Electronic Publication: 2020 Sep 12.
Publication Year :: 2020
Abstract: Channelopathies, neuromuscular junction disorders, and myopathies represent multiple mechanisms by which toxins can affect the peripheral nervous system. These toxins include ciguatoxin, tetrodotoxin, botulinum toxin, metabolic poisons, venomous snake bites, and several medications. These toxins are important to be aware of because they can lead to serious symptoms, disability, or even death, and many can be treated if recognized ear.<br />Competing Interests: Disclosure J. Janecek has nothing to disclose. H. Kushlaf served as a consultant on advisory boards for Alexion, Catalyst Pharmaceuticals, and PTC therapeutics and is on the speakers bureau of Akcea, Catalyst Pharmaceuticals, and Sanofi Genzyme.<br /> (Copyright © 2020 Elsevier Inc. All rights reserved.)