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Study of vitamin E microencapsulation and controlled release from chitosan/sodium lauryl ether sulfate microcapsules.
- Source :
-
Carbohydrate polymers [Carbohydr Polym] 2021 Jan 01; Vol. 251, pp. 116988. Date of Electronic Publication: 2020 Aug 30. - Publication Year :
- 2021
-
Abstract
- Potential benefit of microencapsulation is its ability to deliver and protect incorporated ingredients such as vitamin E. Microcapsule wall properties can be changed by adding of coss-linking agents that are usually considered toxic for application. The microcapsules were prepared by a spray-drying technique using coacervation method, by depositing the coacervate formed in the mixture of chitosan and sodium lauryl ether sulfate to the oil/water interface. All obtained microcapsules suspensions had slightly lower mean diameter compared to the starting emulsion (6.85 ± 0.213 μm), which shows their good stability during the drying process. The choice and absence of cross-linking agents had influence on kinetics of vitamin E release. Encapsulation efficiency of microcapsules without cross-linking agent was 73.17 ± 0.64 %. This study avoided the use of aldehydes as cross-linking agents and found that chitosan/SLES complex can be used as wall material for the microencapsulation of hydrophobic active molecules in cosmetic industry.<br /> (Copyright © 2020. Published by Elsevier Ltd.)
- Subjects :
- Capsules chemistry
Chitosan chemistry
Cosmetics administration & dosage
Cosmetics pharmacokinetics
Cross-Linking Reagents
Delayed-Action Preparations administration & dosage
Delayed-Action Preparations chemistry
Delayed-Action Preparations pharmacokinetics
Dermatologic Agents administration & dosage
Dermatologic Agents pharmacokinetics
Desiccation
Emulsions
Humans
Hydrophobic and Hydrophilic Interactions
In Vitro Techniques
Kinetics
Microscopy, Electron, Scanning
Particle Size
Polyethylene Glycols chemistry
Vitamin E pharmacokinetics
Drug Compounding methods
Vitamin E administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1879-1344
- Volume :
- 251
- Database :
- MEDLINE
- Journal :
- Carbohydrate polymers
- Publication Type :
- Academic Journal
- Accession number :
- 33142560
- Full Text :
- https://doi.org/10.1016/j.carbpol.2020.116988