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[Early outcomes following lung transplantation in patients aged 65 years and older].

Authors :
Avramenko-Bouvier A
Weisenburger G
Jebrak G
Cerceau P
Pellenc Q
Roussel A
Bunel V
Godet C
Messika J
Montravers P
Castier Y
Mal H
Mordant P
Source :
Revue des maladies respiratoires [Rev Mal Respir] 2020 Dec; Vol. 37 (10), pp. 769-775. Date of Electronic Publication: 2020 Nov 04.
Publication Year :
2020

Abstract

Introduction: The number of lung transplantations performed is increasing worldwide. With an improved experience and outcomes, the age of the recipient on its own has ceased to be an absolute contra-indication. We report our first experience with lung transplantation in patients aged 65 years or older.<br />Methods: From January 2014 to March 2019, the files of patients aged 65 years or older undergoing lung transplantation were retrospectively reviewed.<br />Results: During the study period, 241 patients underwent lung transplantation in Bichat hospital (Paris, France), including 25 recipients aged 65 years or older. Underlying diagnoses were interstitial (72%) and obstructive (28%) disease. The rate of single lung transplantation was 80%. Sixteen patients required ECMO assistance during the procedure. Early complications were mostly grade III primary graft dysfunction (12%) and cellular rejection (20%). Overall one-year survival rate was 76%.<br />Conclusion: After a careful selection of the recipients, the early results of our retrospective single center series are encouraging. We continue to consider lung transplantation in rigorously selected recipients of aged 65 years and more.<br /> (Copyright © 2020 SPLF. Published by Elsevier Masson SAS. All rights reserved.)

Details

Language :
French
ISSN :
1776-2588
Volume :
37
Issue :
10
Database :
MEDLINE
Journal :
Revue des maladies respiratoires
Publication Type :
Academic Journal
Accession number :
33158640
Full Text :
https://doi.org/10.1016/j.rmr.2020.08.012