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[Early outcomes following lung transplantation in patients aged 65 years and older].
- Source :
-
Revue des maladies respiratoires [Rev Mal Respir] 2020 Dec; Vol. 37 (10), pp. 769-775. Date of Electronic Publication: 2020 Nov 04. - Publication Year :
- 2020
-
Abstract
- Introduction: The number of lung transplantations performed is increasing worldwide. With an improved experience and outcomes, the age of the recipient on its own has ceased to be an absolute contra-indication. We report our first experience with lung transplantation in patients aged 65 years or older.<br />Methods: From January 2014 to March 2019, the files of patients aged 65 years or older undergoing lung transplantation were retrospectively reviewed.<br />Results: During the study period, 241 patients underwent lung transplantation in Bichat hospital (Paris, France), including 25 recipients aged 65 years or older. Underlying diagnoses were interstitial (72%) and obstructive (28%) disease. The rate of single lung transplantation was 80%. Sixteen patients required ECMO assistance during the procedure. Early complications were mostly grade III primary graft dysfunction (12%) and cellular rejection (20%). Overall one-year survival rate was 76%.<br />Conclusion: After a careful selection of the recipients, the early results of our retrospective single center series are encouraging. We continue to consider lung transplantation in rigorously selected recipients of aged 65 years and more.<br /> (Copyright © 2020 SPLF. Published by Elsevier Masson SAS. All rights reserved.)
- Subjects :
- Age Factors
Age of Onset
Aged
Aged, 80 and over
Female
France epidemiology
Graft Survival
Humans
Lung Diseases, Interstitial mortality
Lung Diseases, Obstructive mortality
Male
Paris epidemiology
Postoperative Period
Primary Graft Dysfunction epidemiology
Retrospective Studies
Survival Rate
Time Factors
Treatment Outcome
Lung Diseases, Interstitial epidemiology
Lung Diseases, Interstitial therapy
Lung Diseases, Obstructive epidemiology
Lung Diseases, Obstructive therapy
Lung Transplantation adverse effects
Lung Transplantation methods
Lung Transplantation mortality
Lung Transplantation statistics & numerical data
Subjects
Details
- Language :
- French
- ISSN :
- 1776-2588
- Volume :
- 37
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Revue des maladies respiratoires
- Publication Type :
- Academic Journal
- Accession number :
- 33158640
- Full Text :
- https://doi.org/10.1016/j.rmr.2020.08.012