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Infective endocarditis - A review of current therapy and future challenges.
- Source :
-
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese [Hellenic J Cardiol] 2021 May-Jun; Vol. 62 (3), pp. 190-200. Date of Electronic Publication: 2020 Nov 08. - Publication Year :
- 2021
-
Abstract
- Etiological, microbiological and epidemiological factors changed over time, but mortality rates remain high in infective endocarditis (IE). Healthcare-associated IE is nowadays responsible for a significant proportion of cases due to increasing numbers of cardiac devices. Cardiac implantable electronic devices, transcatheter aortic valve replacement, and percutaneous valve repair are meanwhile used, especially in old and sick patients. In suspected IE modified Duke criteria, integrating clinical results, imaging, and biomarkers are traditionally applied. Newer imaging technologies such as multi-slice computed tomography, photon-emission computed tomography, and magnetic resonance imaging might add value to conventional echocardiography in diagnosis and management of IE. Treatment consists of long-term antibiotic therapy, infectiological source control and/or cardiac surgery. Recently, antibiotic parenteral outpatient regimens and partial oral treatment strategies were shown to shorten hospital stays in patients suffering from IE. However, it remains unclear how to best select patients for partial oral therapy. This review describes new trends in diagnosing, imaging, and treating IE in a changing patient collective with particular focus on patients with implantable cardiac devices.<br /> (Copyright © 2020 Hellenic Society of Cardiology. Published by Elsevier B.V. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 2241-5955
- Volume :
- 62
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese
- Publication Type :
- Academic Journal
- Accession number :
- 33176209
- Full Text :
- https://doi.org/10.1016/j.hjc.2020.10.007