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Pharyngeal Carriage of Beta-Haemolytic Streptococcus Species and Seroprevalence of Anti-Streptococcal Antibodies in Children in Bouaké, Côte d'Ivoire.

Pharyngeal Carriage of Beta-Haemolytic Streptococcus Species and Seroprevalence of Anti-Streptococcal Antibodies in Children in Bouaké, Côte d'Ivoire.

Authors :
Monemo P
Demba N
Touré FS
Traoré A
Avi C
N'Guessan MA
Tadet JO
Gobey AR
Anoh AE
Diarrassouba A
Tuo MN
Cissé A
Saric J
Utzinger J
Tia H
Kouassi-N'Djeundo J
Becker SL
Akoua-Koffi C
Source :
Tropical medicine and infectious disease [Trop Med Infect Dis] 2020 Nov 27; Vol. 5 (4). Date of Electronic Publication: 2020 Nov 27.
Publication Year :
2020

Abstract

The pharynx of the child may serve as a reservoir of pathogenic bacteria, including beta-haemolytic group A streptococci (GAS), which can give rise to upper airway infections and post-streptococcal diseases. The objective of this study was to determine the prevalence of beta-haemolytic Streptococcus spp. in pharyngeal samples stemming from children aged 3-14 years in Bouaké, central Côte d'Ivoire. Oropharyngeal throat swabs for microbiological culture and venous blood samples to determine the seroprevalence of antistreptolysin O antibodies (ASO) were obtained from 400 children in March 2017. Identification was carried out using conventional bacteriological methods. Serogrouping was performed with a latex agglutination test, while an immunological agglutination assay was employed for ASO titres. The mean age of participating children was 9 years (standard deviation 2.5 years). In total, we detected 190 bacteria in culture, with 109 beta-haemolytic Streptococcus isolates, resulting in an oropharyngeal carriage rate of 27.2%. Group C streptococci accounted for 82.6% of all isolates, whereas GAS were rarely found (4.6%). The ASO seroprevalence was 17.3%. There was no correlation between serology and prevalence of streptococci ( p = 0.722). In conclusion, there is a high pharyngeal carriage rate of non-GAS strains in children from Bouaké, warranting further investigation.

Details

Language :
English
ISSN :
2414-6366
Volume :
5
Issue :
4
Database :
MEDLINE
Journal :
Tropical medicine and infectious disease
Publication Type :
Academic Journal
Accession number :
33261048
Full Text :
https://doi.org/10.3390/tropicalmed5040177