Back to Search
Start Over
The Burden in Caregivers of Multiple Myeloma Patients Undergoing Outpatient Autologous Stem-Cell Transplantation Compared to Inpatient Transplantation.
- Source :
-
Clinical lymphoma, myeloma & leukemia [Clin Lymphoma Myeloma Leuk] 2021 Apr; Vol. 21 (4), pp. e402-e409. Date of Electronic Publication: 2020 Nov 20. - Publication Year :
- 2021
-
Abstract
- Background: The application of different models of autologous stem-cell transplantation (ASCT) in multiple myeloma has demonstrated the feasibility and safety of outpatient-based programs of care. Although several systematic reviews have evaluated the burden of caregivers, only a few studies have included outpatient ASCT.<br />Patients and Methods: The feelings of lack of family support, daily activities, and general health were compared between caregivers of 2 groups of patients with multiple myeloma who underwent inpatient (n = 71) or outpatient (n = 25) ASCT.<br />Results: The 3 features did not significantly differ between the 2 study groups at baseline, before, and 3 months after ASCT. Multivariate modeling showed that the baseline values were significantly related to the changes in study outcomes independent of patient and caregiver characteristics. Other correlates were caregivers' work and patient age for impact on daily activities and disease burden across time for impact on general health (all P < .05).<br />Conclusion: The outpatient model neither improves nor impairs global caregivers' burden compared to standard ASCT care. Further research is needed to confirm this observation and to better assess the burden and quality of life of caregivers and their influence on patient outcomes and quality of life.<br /> (Copyright © 2020 Elsevier Inc. All rights reserved.)
- Subjects :
- Adult
Aged
Female
Hematopoietic Stem Cell Transplantation psychology
Humans
Male
Middle Aged
Multiple Myeloma psychology
Quality of Life
Transplantation, Autologous methods
Transplantation, Autologous psychology
Young Adult
Ambulatory Surgical Procedures psychology
Caregivers psychology
Hematopoietic Stem Cell Transplantation methods
Multiple Myeloma surgery
Subjects
Details
- Language :
- English
- ISSN :
- 2152-2669
- Volume :
- 21
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Clinical lymphoma, myeloma & leukemia
- Publication Type :
- Academic Journal
- Accession number :
- 33288484
- Full Text :
- https://doi.org/10.1016/j.clml.2020.11.011