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Ischemic stroke in COVID-19-positive patients: an overview of SARS-CoV-2 and thrombotic mechanisms for the neurointerventionalist.
- Source :
-
Journal of neurointerventional surgery [J Neurointerv Surg] 2021 Mar; Vol. 13 (3), pp. 202-206. Date of Electronic Publication: 2020 Dec 09. - Publication Year :
- 2021
-
Abstract
- Coronavirus disease 2019 (COVID-19) results from infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It was first reported in Wuhan, China in patients suffering from severe pneumonia and acute respiratory distress syndrome and has now grown into the first pandemic in over 100 years. Patients infected with SARS-CoV-2 develop arterial thrombosis including stroke, myocardial infarction and peripheral arterial thrombosis, all of which result in poor outcomes despite maximal medical, endovascular, and microsurgical treatment compared with non-COVID-19-infected patients. In this review we provide a brief overview of SARS-CoV-2, the infectious agent responsible for the COVID-19 pandemic, and describe the mechanisms responsible for COVID-19-associated coagulopathy. Finally, we discuss the impact of COVID-19 on ischemic stroke, focusing on large vessel occlusion.<br />Competing Interests: Competing interests: None declared.<br /> (© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.)
- Subjects :
- Brain Ischemia therapy
COVID-19 therapy
China epidemiology
Humans
Ischemic Stroke therapy
Pandemics
Thrombolytic Therapy trends
Thrombosis therapy
Brain Ischemia epidemiology
COVID-19 epidemiology
Ischemic Stroke epidemiology
SARS-CoV-2 drug effects
Thrombolytic Therapy methods
Thrombosis epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1759-8486
- Volume :
- 13
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of neurointerventional surgery
- Publication Type :
- Academic Journal
- Accession number :
- 33298508
- Full Text :
- https://doi.org/10.1136/neurintsurg-2020-016794